Two mischievous angels (Matt Damon and Ben Affleck) who were kicked out of heaven, have figured out a way to get back in. Restoring ones soul by entering a new church is a part of the Catholic Dogma, and by restoring their souls, the angels could reenter heaven thus revealing a loophole. But their plan would prove God's imperfection thus erasing everything God had ever created. Jesus' last descendant (Fiorentino) is enlisted by Rufus (Chris Rock), the unknown 13th Apostle to stop the fugitive angels. Along the way, she is aided by two prophets, Jay and Silent Bob.